| Makallé | |
| Native Name Lang: | es |
| Settlement Type: | Town |
| Pushpin Map: | Argentina |
| Pushpin Map Caption: | Location of Makallé in Argentina |
| Coordinates: | -27.2°N -76°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Name1: | Chaco |
| Subdivision Type2: | Department |
| Subdivision Name2: | General Donovan |
| Unit Pref: | Metric |
| Elevation M: | 55 |
| Population Total: | 3812 |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | -3 |
| Postal Code Type: | CPA base |
| Postal Code: | H3514 |
| Area Code Type: | Dialing code |
| Area Code: | +54 3722 |
| Blank Name: | Climate |
| Blank Info: | Cfa |
Makallé is a town in Chaco Province, Argentina. It is the head town of the General Donovan Department.
The town is named after a battle at Mekelle during the Italian invasion of Abyssinia in the 19th century.
The Argentine government established a line of fortresses in Lapachito, Ciervo Petiso y Makallé during the Conquest of Chaco campaign, intended to occupy the indigenous areas in the north-east of Argentina. These fortresses formed the basis of future settlement in the region. By the 1890s the indigenous people had given up the area and it was settled by Italian immigrants amongst others.