Major facilitator superfamily domain-containing protein 9 explained

Major facilitator superfamily domain-containing protein 9 is a protein that in humans is encoded by the MFSD9 gene. It is a potential solute carrier, and called atypical solute carrier[1] since it is not named according to the SLC nomenclature.[2] It is expressed both in central and peripheral organs.[3]

Notes and References

  1. Perland E, Bagchi S, Klaesson A, Fredriksson R . Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression . Open Biology . 7 . 9 . 170142 . September 2017 . 28878041 . 5627054 . 10.1098/rsob.170142 .
  2. Perland E, Fredriksson R . Classification Systems of Secondary Active Transporters . Trends in Pharmacological Sciences . 38 . 3 . 305–315 . March 2017 . 27939446 . 10.1016/j.tips.2016.11.008 .
  3. Perland E, Hellsten SV, Schweizer N, Arapi V, Rezayee F, Bushra M, Fredriksson R . Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice . PLOS ONE . 12 . 10 . e0186325 . 2017 . 29049335 . 5648162 . 10.1371/journal.pone.0186325 . 2017PLoSO..1286325P . free .