| State: | ME |
| Type: | ME |
| Route: | 150 |
| Map Custom: | yes |
| Length Mi: | 50.65 |
| Length Ref: | [1] |
| Established: | 1925 |
| Direction A: | South |
| Terminus A: | in Skowhegan |
| Junction: | |
| Direction B: | North |
| Terminus B: | Dead end in Willimantic |
| Counties: | Somerset, Piscataquis |
| Previous Type: | ME |
| Previous Route: | 149 |
| Next Type: | ME |
| Next Route: | 151 |
State Route 150 (SR 150) is part of Maine's system of numbered state highways, located in Somerset and Piscataquis counties. Its southern terminus is in Skowhegan at the intersection with U.S. Route 2 (US 2). The northern terminus of the route is at a dead end in Willimantic near Sebec Lake.