MafB toxins explained

MafB toxins are exotoxins secreted by pathogenic Neisseria species (including meningococcus and gonococcus).

MafB toxins belong to the category of polymorphic toxins. The N-terminal region of MafB proteins harbors a domain of unknown function named DUF1020 while the C-terminal region is variable and harbors a toxic domain. MafB toxins are involved in interbacterial competition.[1] [2]

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Notes and References

  1. Jamet. Anne. Jousset. Agnès B.. Euphrasie. Daniel. Mukorako. Paulette. Boucharlat. Alix. Ducousso. Alexia. Charbit. Alain. Nassif. Xavier. 2015-01-01. A new family of secreted toxins in pathogenic Neisseria species. PLOS Pathogens. 11. 1. e1004592. 10.1371/journal.ppat.1004592. 1553-7374. 4287609. 25569427 . free .
  2. Arenas. Jesús. de Maat. Vincent. Catón. Laura. Krekorian. Massis. Herrero. Juan Cruz. Ferrara. Flavio. Tommassen. Jan. 2015-08-05. Fratricide activity of MafB protein of N. meningitidis strain B16B6. BMC Microbiology. 15. 156. 10.1186/s12866-015-0493-6. 1471-2180. 4524018. 26242409 . free .

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