| Official Name: | Madre Deus |
| Pushpin Map: | Sao Tome |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location on São Tomé Island |
| Subdivision Type: | Country |
| Subdivision Name: | São Tomé and Príncipe |
| Subdivision Type1: | Island |
| Subdivision Name1: | São Tomé |
| Subdivision Type2: | District |
| Subdivision Name2: | Água Grande |
| Population As Of: | 2012 |
| Population Total: | 2469 |
| Timezone1: | WAT |
| Utc Offset1: | +1 |
| Coordinates: | 0.328°N 6.7215°W |
Madre Deus is a suburb of the city São Tomé in the nation of São Tomé and Príncipe. Its population was 2,469 at the 2012 census.[1] It lies southwest of the city centre, on the road to Trindade.