Macrophomina is a genus of plant pathogens in the fungus family Botryosphaeriaceae, originally described by Franz Petrak in 1923. It contains at least 5 species.
The type species was originally called M. philippinensis, but its current name is Macrophomina phaseolina; it causes charcoal rot disease on many diverse plant species. The former species Macrophomina limbalis has been renamed to Dothiorella limbalis.