Macrobius Cove (Bulgarian: залив Макробий, ‘Zaliv Macrobius’ \'za-liv ma-'kro-biy\) is the 2.8 km wide cove indenting for 3.4 km the west coast of Barison Peninsula, Graham Coast on the Antarctic Peninsula northeast of Eijkman Point and east of Bablon Island. It is part of Leroux Bay. The head of the cove is fed by Chernomen Glacier.
The feature is named after the Roman writer and philosopher Ambrosius Macrobius (4th-5th century) who placed on the world map the southern polar land envisaged by Aristotle.
Macrobius Cove is centred at -65.6181°N -64.1194°W. British mapping in 1971.