| Macky Escalona | |
| Nationality: | Filipino |
| Birth Date: | September 27, 1984 |
| Birth Place: | Quezon City, Philippines |
| Height Ft: | 5 |
| Height In: | 11 |
| Weight Lbs: | 180 |
| High School: | Ateneo (Quezon City) |
| College: | Ateneo |
| Draft Year Pba: | 2007 |
| Draft Round Pba: | 1 |
| Draft Pick Pba: | 10 |
| Draft Team Pba: | Barangay Ginebra Kings |
| Career Start: | 2007 |
| Career End: | 2009 |
| Career Position: | Point guard |
| Team1: | Barangay Ginebra Kings |
| Years1: | 2007–2009 |
| Awards: |
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Mark Anthony Z. "Macky" Escalona (born September 27, 1984) is a Filipino former professional basketball player. He last played for the Barangay Ginebra Kings of the Philippine Basketball Association (PBA). He was drafted 10th overall by the Kings in the 2007 PBA draft.
Escalona played college basketball for the Ateneo Blue Eagles. He also played for Cebuana Lhuiller-Kwarta Padala Moneymen in the Philippine Basketball League before moving to the Barangay Ginebra Kings in the Philippine Basketball Association.
Escalona was one of the finalists in the Myx VJ Search 2008, but failed to win.