MY-5445 explained
MY-5445 is a relatively specific phosphodiesterase 5 inhibitor.[1] [2]
See also
- Vatalanib — a structurally related angiogenesis inhibitor
Notes and References
- Nagendran . J . Archer . SL . Soliman . D . Gurtu . V . Moudgil . R . Haromy . A . St. Aubin . C . Webster . L . Rebeyka . IM . Ross . DB . Light . PE . Dyck . JR . Michelakis . ED . Phosphodiesterase Type 5 is Highly Expressed in the Hypertrophied Human Right Ventricle, and Acute Inhibition of Phosphodiesterase Type 5 Improves Contractility . Circulation . 17 July 2007 . 116 . 3 . 238–48 . 10.1161/circulationaha.106.655266 . 17606845 . 7612061 . free .
- Hagiwara . M . Endo . T . Kanayama . T . Hidaka . H . Effect of 1-(3-Chloroanilino)-4-phenylphthalazine (MY-5445), a Specific Inhibitor of Cyclic GMP Phosphodiesterase, on Human Platelet Aggregation . The Journal of Pharmacology and Experimental Therapeutics . February 1984 . 228 . 2 . 467–71 . 6141286.