Melatonin receptor 1C explained

Melatonin receptor 1C
Symbol:	Mtnr1c
Entrezgene:	30661
Refseq:	AY166825
Uniprot:	Q804I9

Melatonin receptor 1C, also known as MTNR1C, is a protein that is encoded by the Mtnr1c gene. This receptor has been identified in fish, amphibia, and birds, but not in humans.^[1]

Further reading

• Brzezinski A . Brzezinski . Amnon . Melatonin in humans . N. Engl. J. Med. . 336 . 3 . 186–95 . 1997 . 8988899 . 10.1056/NEJM199701163360306 .
• Reppert SM, Weaver DR, Ebisawa T, etal . Cloning of a melatonin-related receptor from human pituitary . FEBS Lett. . 386 . 2–3 . 219–24 . 1996 . 8647286 . 10.1016/0014-5793(96)00437-1 . 38587331 . free .
• Niles LP, Wang J, Shen L, etal . Melatonin receptor mRNA expression in human granulosa cells . Mol. Cell. Endocrinol. . 156 . 1–2 . 107–10 . 2000 . 10612428 . 10.1016/S0303-7207(99)00135-5 . 42730113 .
• Roy D, Angelini NL, Fujieda H, etal . Cyclical regulation of GnRH gene expression in GT1-7 GnRH-secreting neurons by melatonin . Endocrinology . 142 . 11 . 4711–20 . 2001 . 11606436 . 10.1210/en.142.11.4711 . free .
• Ayoub MA, Couturier C, Lucas-Meunier E, etal . Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer . J. Biol. Chem. . 277 . 24 . 21522–8 . 2002 . 11940583 . 10.1074/jbc.M200729200 . free .
• Yuan L, Collins AR, Dai J, etal . MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells . Mol. Cell. Endocrinol. . 192 . 1–2 . 147–56 . 2003 . 12088876 . 10.1016/S0303-7207(02)00029-1 . 54393974 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . free .
• Slominski A, Pisarchik A, Zbytek B, etal . Functional activity of serotoninergic and melatoninergic systems expressed in the skin . J. Cell. Physiol. . 196 . 1 . 144–53 . 2003 . 12767050 . 10.1002/jcp.10287 . 24534729 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Suzuki S, Masui Y, Ohnuki M, etal . Induction of metallothionein synthesis by cilostazol in mice and in human cultured neuronal cell lines . Biol. Pharm. Bull. . 30 . 4 . 791–4 . 2007 . 17409522 . 10.1248/bpb.30.791 . free .

See also

• Melatonin receptor

Further reading

• Classification of protein families - Melatonin receptor type 1C
• Sleep drops with melatonin and lavender in German
• Melatonin receptor genes (mel-1a, mel-1b, mel-1c) are differentially expressed in the avian germ line

Notes and References

1. Sugden D, Davidson K, Hough KA, Teh MT . Melatonin, melatonin receptors and melanophores: a moving story . Pigment Cell Res. . 17 . 5 . 454–60 . 2004 . 15357831 . 10.1111/j.1600-0749.2004.00185.x . free .