Metallothionein 1G Explained

Metallothionein-1G is a protein that in humans is encoded by the MT1G gene.^{[1] [2] [3]}

Further reading

• West AK, Stallings R, Hildebrand CE, etal . Human metallothionein genes: structure of the functional locus at 16q13 . Genomics . 8 . 3 . 513–8 . 1991 . 2286373 . 10.1016/0888-7543(90)90038-V .
• Book: Gedamu L, Varshney U, Jahroudi N, etal . Structure and Expression of the Human Metallothionein Genes . Metallothionein II . 52 . 361–72 . 1987 . 2444457 . 10.1007/978-3-0348-6784-9_34. Experientia Supplementum . 978-3-0348-6786-3 .
• Varshney U, Jahroudi N, Foster R, Gedamu L . Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type-specific expression in response to heavy metals and glucocorticoids . Mol. Cell. Biol. . 6 . 1 . 26–37 . 1987 . 3023827 . 10.1128/MCB.6.1.26. 367480 .
• Pauwels M, van Weyenbergh J, Soumillion A, etal . Induction by zinc of specific metallothionein isoforms in human monocytes . Eur. J. Biochem. . 220 . 1 . 105–10 . 1994 . 8119276 . 10.1111/j.1432-1033.1994.tb18603.x . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Izmailova E, Bertley FM, Huang Q, etal . HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages . Nat. Med. . 9 . 2 . 191–7 . 2003 . 12539042 . 10.1038/nm822 . 26145639 .
• Huang Y, de la Chapelle A, Pellegata NS . Hypermethylation, but not LOH, is associated with the low expression of MT1G and CRABP1 in papillary thyroid carcinoma. . Int. J. Cancer . 104 . 6 . 735–44 . 2003 . 12640681 . 10.1002/ijc.11006 . 26461955 .
• Cui YP, Wang JB, Zhang XY, etal . Using yeast two-hybrid system to identify ECRG2 associated proteins and their possible interactions with ECRG2 gene . World J. Gastroenterol. . 9 . 9 . 1892–6 . 2003 . 12970870 . 4656638 . 10.3748/wjg.v9.i9.1892 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Joshi B, Ordonez-Ercan D, Dasgupta P, Chellappan S . Induction of human metallothionein 1G promoter by VEGF and heavy metals: differential involvement of E2F and metal transcription factors . Oncogene . 24 . 13 . 2204–17 . 2005 . 15735762 . 10.1038/sj.onc.1208206 . free .
• Sun NN, Fastje CD, Wong SS, etal . Dose-dependent transcriptome changes by metal ores on a human acute lymphoblastic leukemia cell line . Toxicology and Industrial Health . 19 . 7–10 . 157–63 . 2005 . 15747776 . 10.1191/0748233703th185oa . 14394243 .
• Pope SN, Lee IR . Yeast two-hybrid identification of prostatic proteins interacting with human sex hormone-binding globulin . J. Steroid Biochem. Mol. Biol. . 94 . 1–3 . 203–8 . 2005 . 15862967 . 10.1016/j.jsbmb.2005.01.007 . 9746088 .

Notes and References

1. Foster R, Jahroudi N, Varshney U, Gedamu L . Structure and expression of the human metallothionein-IG gene. Differential promoter activity of two linked metallothionein-I genes in response to heavy metals . J Biol Chem . 263 . 23 . 11528–35 . Sep 1988 . 10.1016/S0021-9258(18)37990-0 . 3403543 . free .
2. Karin M, Eddy RL, Henry WM, Haley LL, Byers MG, Shows TB . Human metallothionein genes are clustered on chromosome 16 . Proc Natl Acad Sci U S A . 81 . 17 . 5494–8 . Oct 1984 . 6089206 . 391732 . 10.1073/pnas.81.17.5494 . 1984PNAS...81.5494K . free .
3. Web site: Entrez Gene: MT1G metallothionein 1G.