MT-RNR2 explained
| mitochondrially encoded 16S RNA |
| Hgncid: | 7471 |
| Symbol: | MT-RNR2 |
| Altsymbols: | MTRNR2 |
| Entrezgene: | 4550 |
| Uniprot: | Q8IVG9 |
| Chromosome: | MT |
Mitochondrially encoded 16S RNA (often abbreviated as 16S) is the mitochondrial large subunit ribosomal RNA[1] [2] that in humans is encoded by the MT-RNR2 gene. The MT-RNR2 gene also encodes the Humanin polypeptide that has been the target of Alzheimer's disease research.[3]
The 16S rRNA is the mitochondrial homologue of the prokaryotic 23S and eukaryotic nuclear 28S ribosomal RNAs.[4]
See also
Notes and References
- Noda R, Kim CG, Takenaka O, Ferrell RE, Tanoue T, Hayasaka I, Ueda S, Ishida T, Saitou N . 6 . Mitochondrial 16S rRNA sequence diversity of hominoids . The Journal of Heredity . 92 . 6 . 490–496 . 2001 . 11948216 . 10.1093/jhered/92.6.490 . free .
- Nagy A, Wilhelm M, Kovacs G . Mutations of mtDNA in renal cell tumours arising in end-stage renal disease . The Journal of Pathology . 199 . 2 . 237–242 . February 2003 . 12533837 . 10.1002/path.1273 . 35602546 .
- Tajima H, Niikura T, Hashimoto Y, Ito Y, Kita Y, Terashita K, Yamazaki K, Koto A, Aiso S, Nishimoto I . 6 . Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults . Neuroscience Letters . 324 . 3 . 227–231 . May 2002 . 12009529 . 10.1016/S0304-3940(02)00199-4 . 12088367 .
- Eperon IC, Anderson S, Nierlich DP . Distinctive sequence of human mitochondrial ribosomal RNA genes . Nature . 286 . 5772 . 460–467 . July 1980 . 6157106 . 10.1038/286460a0 . 1980Natur.286..460E . 4262269 .
