MPPF explained

MPPF, with the full name 2'-methoxyphenyl-(N-2'-pyridinyl)-p-fluoro-benzamidoethyipiperazine, is a compound that binds to the serotonin-1A receptor. Labeled with fluorine-18 it has been used as a radioligand with positron emission tomography.^[1] It has, e.g., been used to examine the difference in neuroreceptor binding in the human brain across sex and age.^[2]

See also

• WAY-100,635

Notes and References

1. D. Le Bars . High-Yield Radiosynthesis and Preliminary In Vivo Evaluation of p-18FMPPF, a Fluoro Analog of WAY-100635 . . May 1998 . 25 . 4 . 343 - 350 . 10.1016/S0969-8051(97)00229-1 . 9639295 .
2. Nicolas Costes . A18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging . The Journal of Nuclear Medicine . 46 . 12 . December 2005 . 1980 - 1989 . 16330560 . Merlet . I . Ostrowsky . K . Faillenot . I . Lavenne . F . Zimmer . L . Ryvlin . P . Le Bars . D.