MICAL1 explained

NEDD9-interacting protein with calponin homology and LIM domains is a protein that in humans is encoded by the MICAL1 gene.^{[1] [2]}

Interactions

MICAL1 has been shown to interact with NEDD9 and RAB1A.^[3]

Further reading

• Iwata S, Ohashi Y, Kamiguchi K, Morimoto C . Beta 1-integrin-mediated cell signaling in T lymphocytes. . J. Dermatol. Sci. . 23 . 2 . 75–86 . 2000 . 10808124 . 10.1016/S0923-1811(99)00096-1 .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Hattori A, Okumura K, Nagase T, etal . Characterization of long cDNA clones from human adult spleen . DNA Res. . 7 . 6 . 357–66 . 2001 . 11214971 . 10.1093/dnares/7.6.357 . free .
• Terman JR, Mao T, Pasterkamp RJ, etal . MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion . Cell . 109 . 7 . 887–900 . 2002 . 12110185 . 10.1016/S0092-8674(02)00794-8 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Weide T, Teuber J, Bayer M, Barnekow A . MICAL-1 isoforms, novel rab1 interacting proteins . Biochem. Biophys. Res. Commun. . 306 . 1 . 79–86 . 2003 . 12788069 . 10.1016/S0006-291X(03)00918-5 .
• Mungall AJ, Palmer SA, Sims SK, etal . The DNA sequence and analysis of human chromosome 6 . Nature . 425 . 6960 . 805–11 . 2003 . 14574404 . 10.1038/nature02055 . free . 2003Natur.425..805M .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Fischer J, Weide T, Barnekow A . The MICAL proteins and rab1: a possible link to the cytoskeleton? . Biochem. Biophys. Res. Commun. . 328 . 2 . 415–23 . 2005 . 15694364 . 10.1016/j.bbrc.2004.12.182 .
• Bayer M, Fischer J, Kremerskothen J, etal . Identification and characterization of Iporin as a novel interaction partner for rab1 . BMC Cell Biol. . 6 . 15 . 2006 . 1 . 15796781 . 10.1186/1471-2121-6-15 . 1079803 . free .
• Olsen JV, Blagoev B, Gnad F, etal . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . free .
• Jin X, Zhang J, Dai H, etal . Investigation of the four cooperative unfolding units existing in the MICAL-1 CH domain . Biophys. Chem. . 129 . 2–3 . 269–78 . 2007 . 17662518 . 10.1016/j.bpc.2007.06.008 .

Notes and References

1. Suzuki T, Nakamoto T, Ogawa S, Seo S, Matsumura T, Tachibana K, Morimoto C, Hirai H . MICAL, a novel CasL interacting molecule, associates with vimentin . J Biol Chem . 277 . 17 . 14933–41 . Apr 2002 . 11827972 . 10.1074/jbc.M111842200 . free .
2. Web site: Entrez Gene: MICAL1 microtubule associated monoxygenase, calponin and LIM domain containing 1.
3. Weide . Thomas . Teuber Julia . Bayer Michael . Barnekow Angelika . Jun 2003 . MICAL-1 isoforms, novel rab1 interacting proteins . Biochem. Biophys. Res. Commun. . 306 . 1 . 79–86 . United States. 0006-291X. 12788069 . 10.1016/S0006-291X(03)00918-5 .