MFSD1 explained

Major facilitator superfamily domain containing 1 (MFSD1, SMAP) is a protein belonging to the MFS Pfam clan.^[1] It is an Atypical solute carrier.^[2]

It belongs to the major facilitator superfamily MFS Pfam Clan. MFSD1 has been identified in neuronal plasma membranes and lysosomes.^{[3] [4]}

HGNC

25874

MFSD1 belongs to AMTF6.^[5]

Notes and References

1. Perland E, Fredriksson R . Classification Systems of Secondary Active Transporters . Trends in Pharmacological Sciences . 38 . 3 . 305–315 . March 2017 . 27939446 . 10.1016/j.tips.2016.11.008 .
2. Perland E, Hellsten SV, Lekholm E, Eriksson MM, Arapi V, Fredriksson R . The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake . Journal of Molecular Neuroscience . 61 . 2 . 199–214 . February 2017 . 27981419 . 10.1007/s12031-016-0867-8 . 5321710 .
3. Chapel A, Kieffer-Jaquinod S, Sagné C, Verdon Q, Ivaldi C, Mellal M, Thirion J, Jadot M, Bruley C, Garin J, Gasnier B, Journet A . An extended proteome map of the lysosomal membrane reveals novel potential transporters . Molecular & Cellular Proteomics . 12 . 6 . 1572–88 . June 2013 . 23436907 . 3675815 . 10.1074/mcp.M112.021980 . free .
4. Palmieri M, Impey S, Kang H, di Ronza A, Pelz C, Sardiello M, Ballabio A . Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways . Human Molecular Genetics . 20 . 19 . 3852–66 . October 2011 . 21752829 . 10.1093/hmg/ddr306 . free .
5. Perland E, Bagchi S, Klaesson A, Fredriksson R . Characteristics of 29 novel atypical solute carriers of major facilitator superfamily type: evolutionary conservation, predicted structure and neuronal co-expression . en . Open Biology . 7 . 9 . 170142 . September 2017 . 28878041 . 10.1098/rsob.170142 . 5627054 .