MFRP explained

Membrane frizzled-related protein is a protein that in humans is encoded by the MFRP gene.^{[1] [2]}

Further reading

• Metlapally R, Li YJ, Tran-Viet KN, etal . Common MFRP sequence variants are not associated with moderate to high hyperopia, isolated microphthalmia, and high myopia. . Mol. Vis. . 14 . 387–93 . 2008. 18334955 . 2268852 .
• Ayala-Ramirez R, Graue-Wiechers F, Robredo V, etal . A new autosomal recessive syndrome consisting of posterior microphthalmos, retinitis pigmentosa, foveoschisis, and optic disc drusen is caused by a MFRP gene mutation. . Mol. Vis. . 12 . 1483–9 . 2007 . 17167404 .
• Yang L, Yamasaki K, Shirakata Y, etal . Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes. . J. Dermatol. Sci. . 42 . 2 . 111–9 . 2006 . 16442268 . 10.1016/j.jdermsci.2005.12.011 .
• Pauer GJ, Xi Q, Zhang K, etal . Mutation screen of the membrane-type frizzled-related protein (MFRP) gene in patients with inherited retinal degenerations. . Ophthalmic Genet. . 26 . 4 . 157–61 . 2006 . 16352475 . 10.1080/13816810500374425 . 43634962 .
• Mandal MN, Heckenlively JR, Burch T, etal . Sequencing arrays for screening multiple genes associated with early-onset human retinal degenerations on a high-throughput platform. . Invest. Ophthalmol. Vis. Sci. . 46 . 9 . 3355–62 . 2005 . 16123440 . 10.1167/iovs.05-0007 .
• Sundin OH, Leppert GS, Silva ED, etal . Extreme hyperopia is the result of null mutations in MFRP, which encodes a Frizzled-related protein. . Proc. Natl. Acad. Sci. U.S.A. . 102 . 27 . 9553–8 . 2005 . 15976030 . 10.1073/pnas.0501451102 . 1172243 . 2005PNAS..102.9553S . free .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Hayward C, Shu X, Cideciyan AV, etal . Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration. . Hum. Mol. Genet. . 12 . 20 . 2657–67 . 2004 . 12944416 . 10.1093/hmg/ddg289 . free .

Notes and References

1. Katoh M . Molecular cloning and characterization of MFRP, a novel gene encoding a membrane-type Frizzled-related protein . Biochem Biophys Res Commun . 282 . 1 . 116–23 . Mar 2001 . 11263980 . 10.1006/bbrc.2001.4551 .
2. Web site: Entrez Gene: MFRP membrane frizzled-related protein.