METTL14 explained

Methyltransferase like 14 is a protein that in humans is encoded by the METTL14 gene.^[1]

Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J, Edenberg H, Kramer J, Hesselbrock V, Tischfield JA, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP . A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts . Hum. Mol. Genet. . 19 . 12 . 2497–506 . June 2010 . 20332099 . 2876884 . 10.1093/hmg/ddq112 .
Liu J, Yue Y, Han D, Wang X, Fu Y, Zhang L, Jia G, Yu M, Lu Z, Deng X, Dai Q, Chen W, He C . A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation . Nat. Chem. Biol. . 10 . 2 . 93–5 . February 2014 . 24316715 . 3911877 . 10.1038/nchembio.1432 .
Wang X, Feng J, Xue Y, Guan Z, Zhang D, Liu Z, Gong Z, Wang Q, Huang J, Tang C, Zou T, Yin P . Structural basis of N(6)-adenosine methylation by the METTL3-METTL14 complex . Nature . 534 . 7608 . 575–8 . June 2016 . 27281194 . 10.1038/nature18298 . 2016Natur.534..575W . 4448430 .
Śledź P, Jinek M . Structural insights into the molecular mechanism of the m(6)A writer complex . eLife . 5 . September 2016 . 27627798 . 5023411 . 10.7554/eLife.18434 . free .

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