Sabarubicin Explained

Sabarubicin (MEN-10755), a disaccharide analog of doxorubicin, is used for the treatment of small cell lung cancer (SCLC).[1] It has been seen to show superior antitumour efficacy, which is purported to be linked to the activation of p53-independent apoptosis[2]

Notes and References

  1. Web site: Committee for Orphan Medicinal Products . Public summary of positive opinion for orphan designation of sabarubicin for the treatment of small cell lung cancer . 6 October 2009 . European Medicines Agency .
  2. Arcamone FM . Sabarubicin . Topics in Current Chemistry . 283 . 171–89 . 2008 . 23605632 . 10.1007/128_2007_1 .

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