MEMO1 explained
Mediator of cell motility 1 is a protein that in humans is encoded by the MEMO1 gene.[1]
Further reading
- Meira M, Masson R, Stagljar I, Lienhard S, Maurer F, Boulay A, Hynes NE . Memo is a cofilin-interacting protein that influences PLCgamma1 and cofilin activities, and is essential for maintaining directionality during ErbB2-induced tumor-cell migration . Journal of Cell Science . 122 . Pt 6 . 787–97 . March 2009 . 19223396 . 10.1242/jcs.032094 .
- Marone R, Hess D, Dankort D, Muller WJ, Hynes NE, Badache A . Memo mediates ErbB2-driven cell motility . Nature Cell Biology . 6 . 6 . 515–22 . June 2004 . 15156151 . 10.1038/ncb1134 . 23073115 .
- Reymond A, Friedli M, Henrichsen CN, Chapot F, Deutsch S, Ucla C, Rossier C, Lyle R, Guipponi M, Antonarakis SE . From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map . Genomics . 78 . 1–2 . 46–54 . November 2001 . 11707072 . 10.1006/geno.2001.6640 .
- Qiu C, Lienhard S, Hynes NE, Badache A, Leahy DJ . Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site . The Journal of Biological Chemistry . 283 . 5 . 2734–40 . February 2008 . 18045866 . 10.1074/jbc.M703523200 . free .
- Hu YH, Warnatz HJ, Vanhecke D, Wagner F, Fiebitz A, Thamm S, Kahlem P, Lehrach H, Yaspo ML, Janitz M . Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins . BMC Genomics . 7 . 155 . June 2006 . 16780588 . 1526728 . 10.1186/1471-2164-7-155 . free .
- Zaoui K, Honoré S, Isnardon D, Braguer D, Badache A . Memo-RhoA-mDia1 signaling controls microtubules, the actin network, and adhesion site formation in migrating cells . The Journal of Cell Biology . 183 . 3 . 401–8 . November 2008 . 18955552 . 2575782 . 10.1083/jcb.200805107 .
Notes and References
- Web site: Entrez Gene: Mediator of cell motility 1 .