M. Madan Babu Explained

M. Madan Babu
Birth Name:Mohan Madan Babu
Fields:Computational biology
Systems biology
Network biology
Disordered proteins
Regulatory genomics
Workplaces:St. Jude Children's Research Hospital
MRC Laboratory of Molecular Biology
University of Cambridge
National Center for Biotechnology Information
Thesis Title:Evolution of transcriptional regulatory networks
Thesis Url:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616113
Thesis Year:2004
Alma Mater:Anna University (BTech)
University of Cambridge (PhD)
Doctoral Advisor:Sarah Teichmann

M. Madan Babu is an Indian-American computational biologist and bioinformatician. He is the endowed chair in biological data science and director of the center of excellence for data-driven discovery at St. Jude Children's Research Hospital. Previously, he served as a programme leader at the MRC Laboratory of Molecular Biology (LMB).[1]

Early life and education

Babu grew up in Chennai, India.[2] He became interested in learning to program as a young child when his father brought home a personal computer. Babu was introduced to biotechnology as a high school student. He obtained his Bachelor of Technology degree from Anna University, where he was introduced to the field of computational biology. Babu obtained his PhD in computational genomics at the University of Cambridge supervised by Sarah Teichmann in 2004.[3]

Career and research

After his PhD, Babu was a postdoctoral researcher at the National Center for Biotechnology Information (NCBI), at the National Institute of Health (NIH) in Bethesda, Maryland with Aravind L. Iyer. In 2006, he became a group leader at the MRC Laboratory of Molecular Biology in Cambridge, UK. In July 2020, Babu joined the faculty of St. Jude Children's Research Hospital as the endowed chair in biological data science in the structural biology department and director of the center of excellence for data-driven discovery.[4]

Babu's research focuses on understanding the regulation of cellular systems at varying scales, including molecular, system, and genomic levels. He also studies the effects of such regulation on genome evolution.[5] In particular, his research group studies G protein-coupled receptors and intrinsically disordered proteins using a combination of computational biology and experimental biology approaches.[6]

Babu serves as chief editor of the journal Molecular Systems Biology.[7]

Awards and honours

Notes and References

  1. The Transcriptional Landscape of the Mammalian Genome. Science. 309. 5740. 2005. 1559–1563. 0036-8075. 10.1126/science.1112014. 16141072. Various. 2005Sci...309.1559F. 8712839.
  2. Web site: 2018 ISCB Innovator Award: M. Madan Babu. 2020-11-21. iscb.org.
  3. PhD. University of Cambridge. Evolution of transcriptional regulatory networks. Madan Babu. Mohan. 2004. . cam.ac.uk. 890159758.
  4. Web site: M. Madan Babu joins St. Jude Children's Research Hospital as endowed chair in biological data science. 2020-11-21. stjude.org. en.
  5. Web site: Kiessling. Tilmann. Molecular Systems Biology appoints M. Madan Babu as new Chief Editor. 2019. 2020-11-22. embo.org. en-gb.
  6. 2016. Illuminating the Dark Proteome. Anon. Cell. en. 166. 5. 1074–1077. 10.1016/j.cell.2016.08.012. 0092-8674. 27565336. free.
  7. Lemberger. Thomas. Babu. M Madan. Enabling next generation systems biology: a conversation with M. Madan Babu. Molecular Systems Biology. 15. 12. 2019. e9376. 1744-4292. 10.15252/msb.199376. 31885204 . 6894041.
  8. News: 4 November 2009. EMBO recognizes talented young group leaders in Europe. ifom.eu.
  9. Web site: Biochemical Society 2010 Award Winners.
  10. Web site: Genetics Society Balfour Lecture.
  11. Royal Society of Chemistry Molecular BioSystems Award 2011. Molecular BioSystems . 2011 . 7 . 2 . 281 . 10.1039/C0MB90043E .
  12. Web site: The Colworth Medal. biochemistry.org.
  13. Web site: 2014-09-03. Melina Schuh and M. Madan Babu awarded Lister Research Prizes. 2020-11-21. mrc-lmb.cam.ac.uk. MRC Laboratory of Molecular Biology. en-GB.
  14. Web site: Madan Babu Archives.
  15. Web site: The Protein Society announces its 2014 award recipients. 2021-04-13. EurekAlert!. en.
  16. Web site: Unstructured proteins: cellular complexity and human diseases . Royal Society. London. Anon. 2015. 2020-11-21. royalsociety.org. en-gb.
  17. News: Patterson. Holly. 29 November 2016. Code-cracking: using computers to understand life's source codes. Inside Science.
  18. Web site: Three LMB scientists elected to EMBO membership. 2020-11-21. mrc-lmb.cam.ac.uk. 23 May 2016 . MRC Laboratory of Molecular Biology. en-GB.
  19. Web site: The United Kingdom's Top Scientists and Engineers Honoured by the Inaugural Blavatnik Awards for Young Scientists . Blavatnik Awards for Young Scientists. 2020-11-22. blavatnikawards.org.
  20. Fogg. Christiana N.. Kovats. Diane E.. Shamir. Ron. 2018 ISCB Innovator Award recognizes M. Madan Babu. PLOS Computational Biology. 14. 6. 2018. e1006164. 1553-7358. 10.1371/journal.pcbi.1006164. 29879101 . 5991638. 2018PLSCB..14E6164F . free .
  21. Web site: Kiessling. Tilmann . M. Madan Babu and Paola Picotti honoured with EMBO Gold Medal. 2019. 2020-11-21. embo.org. en-gb.
  22. Web site: 50 outstanding biomedical and health scientists elected to prestigious Academy of Medical Sciences Fellowship The Academy of Medical Sciences. 2021-05-16. acmedsci.ac.uk.
  23. Web site: Madan Babu Mohan . 2023-05-25 . The Royal Society.

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