| Mézières-sur-Ponthouin | |
| Commune Status: | Commune |
| Arrondissement: | Mamers |
| Canton: | Mamers |
| Insee: | 72196 |
| Postal Code: | 72290 |
| Mayor: | Guy Cosme[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Maine Saosnois |
| Coordinates: | 48.1936°N 0.3006°W |
| Elevation Min M: | 55 |
| Elevation Max M: | 131 |
| Area Km2: | 17.88 |
Mézières-sur-Ponthouin (in French pronounced as /mezjɛʁ syʁ pɔ̃twɛ̃/) is a commune in the Sarthe department in the region of Pays de la Loire in north-western France.