| Mézières-en-Gâtinais | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason_Ville_fr_Mézières-en-Gâtinais(45).svg |
| Arrondissement: | Montargis |
| Canton: | Lorris |
| Insee: | 45205 |
| Postal Code: | 45270 |
| Mayor: | Alain Thillou[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Canaux et Forêts en Gâtinais |
| Coordinates: | 48.0358°N 2.4908°W |
| Elevation Min M: | 92 |
| Elevation Max M: | 111 |
| Area Km2: | 9.86 |
| Demonym: | Macériens |
Mézières-en-Gâtinais (pronounced as /fr/; literally "Mézières in Gâtinais") is a commune in the Loiret department in north-central France.