| Ménessaire | |
| Commune Status: | Commune |
| Arrondissement: | Beaune |
| Canton: | Arnay-le-Duc |
| Insee: | 21403 |
| Postal Code: | 21430 |
| Mayor: | Nadine Rateau[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | CC du Pays d'Arnay Liernais |
| Coordinates: | 47.1358°N 4.1486°W |
| Elevation M: | 550 |
| Elevation Min M: | 393 |
| Elevation Max M: | 721 |
| Area Km2: | 14.91 |
Ménessaire (in French pronounced as /menəsɛʁ/, also in French pronounced as /menesɛʁ/; Burgundian: Meunsiâre) is a rural commune in the Côte-d'Or department in the Bourgogne-Franche-Comté region in central-east France.
A Côte-d'Or exclave on the border between the Nièvre and Saône-et-Loire departments, Ménessaire is part of Morvan Regional Natural Park. It comprises the Mont de Gien, the highest point in Côte-d'Or, at 721 metres.