| Mário Matos | |
| Fullname: | Mário Santos de Matos |
| Birth Date: | 21 June 1988 |
| Birth Place: | Brussels, Belgium |
| Height: | 1.85 m |
| Position: | Goalkeeper |
| Youthyears1: | 2005–2006 |
| Youthclubs1: | Anderlecht |
| Years1: | 2006–2010 |
| Caps1: | 14 |
| Goals1: | 0 |
| Years2: | 2010–2013 |
| Caps2: | 7 |
| Goals2: | 0 |
| Years3: | 2013–2014 |
| Caps3: | 2 |
| Goals3: | 0 |
| Club-Update: | 17 December 2015 |
Mário Santos de Matos (born 21 June 1988) is a Portuguese professional footballer who last played for União Madeira as a goalkeeper. He also holds Belgian citizenship.