| Mária Holešová | |
| Nationality: | Slovak |
| Birth Date: | 24 April 1993 |
| Birth Place: | Bytča, Slovakia |
| Position: | Left wing |
| Currentclub: | Mosonmagyaróvári KC SE |
| Years1: | –2013 |
| Clubs1: | MHK Bytča |
| Years2: | 2013–2018 |
| Clubs2: | IUVENTA Michalovce |
| Years3: | 2018–2019 |
| Clubs3: | RK Podravka Koprivnica |
| Years4: | 2019–2021 |
| Clubs4: | Mosonmagyaróvári KC SE |
| Nationalyears1: | 2015– |
| Nationalteam1: | Slovakia |
Mária Holešová (born 24 April 1993)[1] is a Slovak handballer who plays for Mosonmagyaróvári KC SE and the Slovakia national team.