Lysophosphatidylserine Explained

Lysophosphatidylserine is a lysophospholipid which triggers TLR 2.

A recent study showed that it does not stimulate normal leukocytes.[1] It also enhances glucose transport, lowering blood glucose levels while leaving secretion of insulin unaffected.[2]

References

  1. Park KS, Lee HY, Kim MK, Shin EH, Bae YS . Lysophosphatidylserine stimulates leukemic cells but not normal leukocytes . Biochemical and Biophysical Research Communications . 333 . 2 . 353–8 . Jul 2005 . 15946646 . 10.1016/j.bbrc.2005.05.109 .
  2. Yea K, Kim J, Lim S, Kwon T, Park HS, Park KS, Suh PG, Ryu SH . Lysophosphatidylserine regulates blood glucose by enhancing glucose transport in myotubes and adipocytes . Biochemical and Biophysical Research Communications . 378 . 4 . 783–8 . Jan 2009 . 19063864 . 10.1016/j.bbrc.2008.11.122 .