| Lyoffans | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Lyoffans 70.svg |
| Coordinates: | 47.6486°N 6.5819°W |
| Insee: | 70313 |
| Postal Code: | 70200 |
| Arrondissement: | Lure |
| Canton: | Lure-2 |
| Elevation Min M: | 293 |
| Elevation Max M: | 375 |
| Area Km2: | 4.49 |
Lyoffans is a commune in the Haute-Saône department in the region of Bourgogne-Franche-Comté in eastern France.
The river Clairegoutte joins the Rognon here.