| Npc: | LUX |
| Npcname: | Luxembourg Paralympic Committee |
| Games: | Summer Paralympics |
| Year: | 2016 |
| Location: | Rio de Janeiro |
| Competitors: | 3 |
| Sports: | 2 |
| Flagbearer: | Joel Wagener |
| Gold: | 0 |
| Silver: | 0 |
| Bronze: | 0 |
| Appearances: | auto |
Luxembourg competed at the 2016 Summer Paralympics in Rio de Janeiro, Brazil, from 7 September to 18 September 2016. Tom Habscheid earned the best result for the country with a 7th place in men's shot put F42.
See main article: article and Athletics at the 2016 Summer Paralympics.
See main article: article and Cycling at the 2016 Summer Paralympics.
| Athlete | Event | Time | Rank | |
|---|---|---|---|---|
| align=left rowspan=2 | Luciano Fratini | Men's road time trial H3 | 34:05.77 | 12 |
| Men's road race H3 | 1:52:52 | 10 | ||
| align=left rowspan=2 | Joel Wagener | Men's road time trial H4 | 31:59.40 | 11 |
| Men's road race H4 | 1:41:11 | 11 |