Lunamarine Explained

Lunamarine (punarnavine) is a quinolone alkaloid present in Boerhavia diffusa (punarnava).

The compound has shown some in vitro anticancer,[1] antiestrogenic,[2] immunomodulatory,[3] and anti-amoebic activity (particularly against Entamoeba histolytica).[4]

Notes and References

  1. Manu K.A. . Kuttan G. . Punarnavine induces apoptosis in B16F-10 melanoma cells by inhibiting NF-kappaB signaling . Asian Pacific Journal of Cancer Prevention . 2009 . 10 . 6 . 1031–1037 . 20192578.
  2. Sreeja S. . Sreeja S. . An in vitro study on antiproliferative and antiestrogenic effects of Boerhaavia diffusa L. extracts . Journal of Ethnopharmacology . 2009 . 126 . 2 . 221–225 . 10.1016/j.jep.2009.08.041 . 19723573.
  3. Manu K.A. . Kuttan G. . Immunomodulatory activities of Punarnavine, an alkaloid from Boerhaavia diffusa . Immunopharmacology and Immunotoxicology . 2009 . 31 . 3 . 377–387 . 10.1080/08923970802702036 . 19555203. 2066582 .
  4. Sohni YR. . Kaimal P. . Bhatt RM. . Jan 1995 . The antiamoebic effect of a crude drug formulation of herbal extracts against Entamoeba histolytica in vitro and in vivo . . 45 . 1 . 43–52 . 10.1016/0378-8741(94)01194-5. 7739226 .

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