Luliconazole Explained

Iupac Name:	(2E)-[(4''R'')-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene](1H-imidazol-1-yl)acetonitrile
Tradename:	Luzu, Luzarn, Lulicon, LULY, Zyluli,Luris
Legal Status:	Rx-only
Routes Of Administration:	Topical
Protein Bound:	>99%^[1]
Atc Prefix:	D01
Atc Suffix:	AC18
Cas Number:	187164-19-8
Unii:	RE91AN4S8G
Pubchem:	3003141
Chemspiderid:	2273807
Smiles:	C1[C@H](S/C(=C(\C#N)/N2C=CN=C2)/S1)C3=C(C=C(C=C3)Cl)Cl
Stdinchi:	1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1
Stdinchikey:	YTAOBBFIOAEMLL-REQDGWNSSA-N
C:	14
H:	9
Cl:	2
N:	3
S:	2

Luliconazole, trade names Luzu among others, is an imidazole antifungal medication.^[2] As a 1% topical cream, It is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by dermatophytes such as Trichophyton rubrum, Microsporum gypseum,^[3] and Epidermophyton floccosum.

Notes and References

1. Web site: LUZU (luliconazole) Cream, 1%. Full Prescribing Information.. Valeant Pharmaceuticals North America LLC. 1 October 2015.
2. Gupta AK, Daigle D . A critical appraisal of once-daily topical luliconazole for the treatment of superficial fungal infections . Infection and Drug Resistance . 9 . 1–6 . 2016 . 26848272 . 4723097 . 10.2147/IDR.S61998 . free .
3. News: FDA approves luliconazole for tinea pedis. November 19, 2013. 14 January 2014. https://web.archive.org/web/20140116083218/http://formularyjournal.modernmedicine.com/formulary-journal/news/fda-approves-luliconazole-tinea-pedis. 16 January 2014. dead.