| Luján de Cuyo | |
| Native Name: | Departamento Luján de Cuyo |
| Settlement Type: | Department |
| Coordinates: | -33.5°N -120°W |
| Subdivision Type: | Country |
| Subdivision Name: | Argentina |
| Established Title: | Established |
| Established Date: | May 11, 1855 |
| Founder: | ? |
| Seat Type: | Seat |
| Seat: | Luján de Cuyo |
| Leader Title: | Mayor |
| Leader Name: | Esteban Allasino |
| Unit Pref: | Metric |
| Area Total Km2: | 4,847 |
| Population Total: | 104,470 |
| Population Density Km2: | auto |
| Population Demonym: | lujanense |
| Postal Code Type: | Postal Code |
| Postal Code: | M5507 |
| Postal2 Code Type: | IFAM |
| Postal2 Code: | MZA008 |
| Area Code Type: | Area Code |
| Area Code: | 02614 |
| Blank Name Sec1: | Patron saint |
| Blank Info Sec1: | Nuestra Señora de Luján de Cuyo |
Luján de Cuyo is a department located in the northwest of Mendoza Province in Argentina.
The provincial subdivision has a population of about 104,000 inhabitants in an area of, and its capital city is Luján de Cuyo, which is located around from the Federal Capital.