| Luis de los Santos | |
| Position: | Pitcher |
| Birth Date: | 1 November 1977 |
| Birth Place: | Santo Domingo, Dominican Republic |
| Bats: | Right |
| Throws: | Right |
| Debutleague: | MLB |
| Debutdate: | July 20 |
| Debutyear: | 2002 |
| Debutteam: | Tampa Bay Devil Rays |
| Finalleague: | MLB |
| Finaldate: | July 31 |
| Finalyear: | 2002 |
| Finalteam: | Tampa Bay Devil Rays |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 0–3 |
| Stat2label: | Earned run average |
| Stat2value: | 11.57 |
| Stat3label: | Strikeouts |
| Stat3value: | 7 |
| Teams: | |
Luis de los Santos (November 1, 1977), is a former Major League Baseball pitcher who played in . He played for the Tampa Bay Devil Rays.