Luis Asprilla should not be confused with Luis Carlos Asprilla.
| Luis Asprilla | |
| Fullname: | Luis Alberto Asprilla Mosquera |
| Birth Date: | 6 December 1977 |
| Birth Place: | Cali, Colombia |
| Position: | Defender |
| Years1: | 1996–1997 |
| Years2: | 1998–1999 |
| Years3: | 2000 |
| Years4: | 2000–2004 |
| Years5: | 2004–2005 |
| Years6: | 2006 |
| Years7: | 2007 |
| Years8: | 2007 |
| Years9: | 2008 |
| Years10: | 2008 |
| Years11: | 2009 |
| Years12: | 2010 |
| Years13: | 2011 |
| Clubs11: | Depor |
| Clubs12: | Alianza Atlético |
| Clubs13: | Bogotá |
| Caps2: | 7 |
| Caps3: | 19 |
| Caps4: | 121 |
| Caps5: | 25 |
| Caps6: | 39 |
| Caps7: | 7 |
| Caps8: | 13 |
| Caps9: | 9 |
| Caps11: | 0 |
| Caps12: | 38 |
| Goals2: | 1 |
| Goals3: | 2 |
| Goals4: | 8 |
| Goals5: | 1 |
| Goals6: | 5 |
| Goals7: | 0 |
| Goals8: | 0 |
| Goals9: | 1 |
| Goals11: | 0 |
| Goals12: | 2 |
| Nationalyears1: | 2001 |
| Nationalteam1: | Colombia |
| Nationalcaps1: | 1 |
| Nationalgoals1: | 0 |
| Pcupdate: | December 26, 2012 |
Luis Asprilla (born 6 December 1977) is a retired Colombian football defender.
He played for the Colombia national team in 2001. He has played outside Colombia for Olimpo de Bahía Blanca in Argentina and Emelec in Ecuador.