| Type: | archbishop |
| Honorific-Prefix: | Most Reverend |
| Luca Mannelli | |
| Bishop of Fano | |
| Church: | Catholic Church |
| Predecessor: | Pietro III |
| Successor: | Leone II |
| Consecration: | 5 November 1347 |
| Consecrated By: | Pope Innocent VI |
| Death Date: | 1362 |
| Previous Post: | Bishop of Zeitun (1344–1347) Bishop of Osimo (1347–1358) |
| Nationality: | Italian |
Luca Manelli (circa 1265 – 1362) was an Italian classicist and archbishop.
He was born in Florence to a prominent family. He joined the Dominican order circa 1280. His erudition brought him into the circle of Pope Clement VI in Avignon. There he published some of the epistles of Seneca and wrote a treatise on moral philosophy. He was appointed as bishop of Osimo in 1347, and later Fano in 1358, where he died.[1]