| Order: | 149th Doge of the Republic of Genoa |
| Term Start1: | January 22, 1728 |
| Term End1: | January 22, 1730 |
| Predecessor1: | Gerolamo Veneroso |
| Successor1: | Francesco Maria Balbi |
| Birth Date: | 1675 |
| Birth Place: | Genoa, Republic of Genoa |
| Death Date: | 1750 |
| Death Place: | Genoa, Republic of Genoa |
Luca Grimaldi (Genoa, 1675 - Genoa, 1750) was the 149th Doge of the Republic of Genoa and king of Corsica.
During his mandate as Doge. Grimaldi promoted two public works for the Genoese city and the readjustment of the donkey-back water conduit for the supply of the republican capital. He ended the dogate on January 22, 1730, but would continue to serve the republic in other state jobs. Grimaldi died in Genoa in 1750.