| Louse Creek | |
| Name Other: | Tributary to Niobrara River |
| Map Size: | 300 |
| Pushpin Map: | USA Nebraska#USA |
| Pushpin Map Size: | 300 |
| Pushpin Map Caption: | Location of Louse Creek mouth |
| Pushpin Map Alt: | Map of Louse Creek mouth location |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Nebraska |
| Subdivision Type3: | County |
| Subdivision Name3: | Holt |
| Length: | 8.19miles[1] |
| Discharge1 Location: | Niobrara River |
| Discharge1 Avg: | 2.84cuft/s at mouth with Niobrara River[2] |
| Source1: | confluence of East and West Branches of Louse Creek |
| Source1 Location: | about 4 miles west of Dorsey, Nebraska |
| Source1 Coordinates: | 42.6789°N -98.4384°W[3] |
| Source1 Elevation: | 1705feet |
| Mouth: | Niobrara River |
| Mouth Location: | about 0.5 miles north-northeast of Redbird, Nebraska |
| Mouth Coordinates: | 42.7706°N -98.4379°W |
| Mouth Elevation: | 1398feet |
| Progression: | Niobrara River → Missouri River → Mississippi River → Gulf of Mexico |
| River System: | Niobrara |
| Tributaries Left: | West Branch Louse Creek |
| Tributaries Right: | East Branch Louse Creek |
| Bridges: | 887th Road, 888th Road, 893rd Road |
Louse Creek is a 8.29miles long third-order tributary to the Niobrara River in Holt County, Nebraska.
Louse Creek begins at the confluence of East and West Branches of Louse Creek about west of Dorsey, Nebraska in Holt County and then flows generally north-northwest to join the Niobrara River about north-northeast of Redbird, Nebraska.[3]
Louse Creek drains of area, receives about of precipitation, and is about 4.18% forested.[2]