| Loupiac-de-la-Réole | |
| Commune Status: | Commune |
| Arrondissement: | Langon |
| Canton: | Le Réolais et Les Bastides |
| Insee: | 33254 |
| Postal Code: | 33190 |
| Mayor: | Emmanuel Gil[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Réolais en Sud Gironde |
| Coordinates: | 44.5486°N -0.0458°W |
| Elevation M: | 52 |
| Elevation Min M: | 13 |
| Elevation Max M: | 65 |
| Area Km2: | 5.32 |
Loupiac-de-la-Réole (in French pronounced as /lupjak də la ʁeɔl/, literally Loupiac of La Réole; Occitan (post 1500);: Lopiac de la Rèula) is a commune in the Gironde department in Nouvelle-Aquitaine in southwestern France.