| Louise Christine of Stolberg-Stolberg-Ortenberg | |
| Consort: | yes |
| Succession: | Duchess consort of Saxe-Weissenfels |
| Reign: | 1712-1736 |
| House: | Stolberg |
| Father: | Christoph Louis I, Count of Stolberg-Stolberg-Ortenberg |
| Mother: | Louise Christine of Hesse-Darmstadt |
| Spouse: | John George III, Count of Mansfeld-Eisleben Christian, Duke of Saxe-Weissenfels |
| Birth Date: | 21 January 1675 |
| Birth Place: | Ortenberg |
Louise Christine of Stolberg-Stolberg-Ortenberg (21 January 1675 - 16 May 1738), was a German noblewoman member of the House of Stolberg and by her two marriages Countess of Mansfeld-Eisleben and Duchess of Saxe-Weissenfels.
Born in Ortenberg, she was the sixth of the eight children born from the marriage of Christoph Louis I, Count of Stolberg-Stolberg-Ortenberg and Countess Louise Christine of Hesse-Darmstadt. From her seven older and younger siblings, four survive adulthood: Georg, Hereditary Prince of Stolberg-Stolberg-Ortenberg, Sophie Eleonore, Christoph Frederick and Jost Christian.
In Stolberg on 13 December 1704, Louise Christine married firstly John George III, Count of Mansfeld-Eisleben. They had no children. Count John George III died on 1 January 1710.
In Stolberg on 11 May 1712, Louise Christine married secondly Christian, Duke of Saxe-Weissenfels. For this occasion, the Elector Frederick August I of Saxony, had the Weissenfelser Hunt Cup (der Weißenfelser Jagdpokal) made as a gift for the couple. It was a costly and complex masterpiece of gold forging executed by the brothers Johann Melchior and George Christoph Dinglinger; it took as its artistic inspiration the duke's preference for the hunt. The cup stayed in the possession of the ducal house of Saxe-Weissenfels until it became extinct; after this, it again came into the possession of the Electorate of Saxony and can be admired today in the Green Vault (de: Grünes Gewölbe). They had no children.
Louise Christine died in Weissenfels aged 63, having survived her second husband by twenty-three months. She was buried in the Schlosskirche, Weissenfels.
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