Clotrimazole/betamethasone dipropionate explained

Type:combo
Component1:Clotrimazole
Class1:Azole antifungal
Component2:Betamethasone dipropionate
Class2:Corticosteroid
Tradename:Lotrisone
Dailymedid:Clotrimazole and betamethasone
Routes Of Administration:Topical
Atc Prefix:D01
Atc Suffix:AC20
Legal Us:Rx-only
Kegg:D10300

Clotrimazole/betamethasone dipropionate, sold under the brand name Lotrisone among others, is a topical medication used for the treatment of fungal infections of the feet, groin, and body in people 17 years of age and older.[1] It is a combination of clotrimazole and betamethasone dipropionate. It is applied to the skin.

Common side effects include paresthesia, rash, edema, and secondary infections.

In 2021, it was the 274th most commonly prescribed medication in the United States, with more than 900,000 prescriptions.[2] [3]

Medical uses

Clotrimazole/betamethasone dipropionate is indicated for the topical treatment of symptomatic inflammatory tinea pedis, tinea cruris, and tinea corporis due to Epidermophyton floccosum, Trichophyton mentagrophytes, and Trichophyton rubrum in people 17 years of age and older.[4]

Society and culture

Legal status

Clotrimazole/betamethasone dipropionate cream was approved for medical use in the United States in July 1984,[5] and the lotion was approved for use in the United States in December 2000.[6]

External links

Notes and References

  1. Greenberg HL, Shwayder TA, Bieszk N, Fivenson DP . Clotrimazole/betamethasone diproprionate: a review of costs and complications in the treatment of common cutaneous fungal infections . Pediatric Dermatology . 19 . 1 . 78–81 . 2002 . 11860579 . 10.1046/j.1525-1470.2002.00027.x . 23472426 .
  2. Web site: The Top 300 of 2021 . ClinCalc . 14 January 2024 . 15 January 2024 . https://web.archive.org/web/20240115223848/https://clincalc.com/DrugStats/Top300Drugs.aspx . live .
  3. Web site: Betamethasone; Clotrimazole - Drug Usage Statistics . ClinCalc . 14 January 2024 . 15 January 2024 . https://web.archive.org/web/20240115224015/https://clincalc.com/DrugStats/Drugs/BetamethasoneClotrimazole . live .
  4. Web site: Lotrisone- clotrimazole and betamethasone dipropionate cream . DailyMed . 14 June 2019 . 13 April 2020 . 28 August 2021 . https://web.archive.org/web/20210828041557/https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40ec029d-8af0-4f8f-bea1-1d38779ec232 . live .
  5. Web site: Lotrisone: FDA-Approved Drugs . U.S. Food and Drug Administration (FDA) . 13 April 2020 . 1 October 2020 . https://web.archive.org/web/20201001142158/https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=018827 . live .
  6. Web site: Drug Approval Package: Lotrisone (Clotrizazole & Betamethasone Dipropionate) NDA #020010 . U.S. Food and Drug Administration (FDA) . 8 September 2004 . 13 April 2020 . 7 April 2021 . https://web.archive.org/web/20210407003255/https://www.accessdata.fda.gov/drugsatfda_docs/nda/2000/20010_Lotrisone.cfm . live .

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