| Lothar Prehn | |
| Birth Date: | 1946 10, df=yes |
| Position: | defender |
| Years1: | 1966–1967? |
| Clubs1: | Duisburger FV 08 |
| Years2: | 1969–1970 |
| Clubs2: | VfB Speldorf |
| Years3: | 1970–1976 |
| Clubs3: | Bayer 05 Uerdingen |
| Years4: | 1977?–1978 |
| Clubs4: | TuS Grevenbroich |
Lothar Prehn (6 October 1946 – 6 April 2024[1]) was a German football defender.