| Official Name: | Los Santos |
| Settlement Type: | Municipality |
| Flag Size: | 150 |
| Coordinates: | 40.5503°N -5.8°W |
| Subdivision Type: | Country |
| Subdivision Name: | Spain |
| Subdivision Type1: | Autonomous community |
| Subdivision Name1: | Castile and León |
| Subdivision Type2: | Province |
| Subdivision Name2: | Salamanca |
| Subdivision Type3: | Comarca |
| Subdivision Name3: | Comarca de Guijuelo |
| Subdivision Type4: | Subcomarca |
| Subdivision Name4: | Entresierras |
| Leader Party: | People's Party |
| Leader Title: | Mayor |
| Leader Name: | Juan Morato Morato |
| Area Footnotes: | [1] |
| Area Total Km2: | 44 |
| Elevation M: | 948 |
| Population Density Km2: | auto |
| Timezone: | CET |
| Utc Offset: | +1 |
| Timezone Dst: | CEST |
| Utc Offset Dst: | +2 |
| Postal Code Type: | Postal code |
| Postal Code: | 37768 |
Los Santos is a municipality located in the province of Salamanca, Castile and León, Spain.