This is a list of the Los Premios MTV Latinoamérica winners and nominees for Best Solo Artist.
| Year | Winner | Other nominees | |
|---|---|---|---|
| 2002 | Best Male Artist: Juanes | ||
| Best Female Artist: Shakira | |||
| 2003 | Natalia Lafourcade | ||
| 2004 | Julieta Venegas | ||
| 2005 | Best Male Artist: Juanes | ||
| Best Female Artist: Shakira | |||
| 2006 | Julieta Venegas | ||
| 2007 | Belinda | ||
| 2008 | Juanes | ||
| 2009 | Paulina Rubio |