| Loreto Secondary School, Kilkenny | |
| Native Name: | Irish: Meánscoil Loreto |
| Motto: | Cruci dum spiro fido |
| Motto Translation: | Throughout my life, I shall place my hope in the Cross |
| Founder: | M.M. Scholastica Somers, Loreto Sisters |
| Trust: | Loreto Education Trust |
| Location: | Kilkenny |
| Country: | Ireland |
| Coordinates: | 52.65944, -7.26116 |
| Type: | Voluntary Secondary School |
| Religion: | Roman Catholic |
| Colours: | Royal blue and grey |
| Age Range: | 11-19 |
| Gender: | Girls |
| Chairperson: | Tony Joyce |
| Principal: | Colm Keher |
| Students: | 1,020 |
| Address: | Granges Road, R95 W2NV |
Loreto Secondary School, Kilkenny is a Roman Catholic voluntary secondary school for girls in Kilkenny, Ireland. It was founded by the Sisters of Loreto in 1868 as a boarding and day school for girls. Its first home was, for a brief time, in Patrick Street. The sisters and school then moved to the building that now is home to the Good Shepherd Centre. A new campus was completed on the Granges Road in 1980 when the school transferred to its present location. In 1984 the boarding section was discontinued.