Lorajmine Explained

Lorajmine (17-monochloroacetylajmaline) is a drug that is a potent sodium channel blocker (more specifically, a class Ia antiarrhythmic agent) that was used for treating arrhythmia.[1] [2] [3] It is derived from ajmaline, an alkaloid from the roots of Rauvolfia serpentina, by synthetically adding a chloroacetate residue.

Notes and References

  1. http://www.online-medical-dictionary.org/?q=Lorajmine Medical Dictionary Online: Lorajmine
  2. [World Health Organization]
  3. Sanna G, Meoli P, Bianchini C, Rovelli F . Antiarrhythmic effectiveness of propafenone compared to lorajmine in ventricular arrhythmias. Controlled clinical trial . Giornale Italiano di Cardiologia . 13 . 3 . 145–51 . 1983 . 6350090 .

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