London1 novel CoV/2012 explained
London1_novel CoV/2012 is a coronavirus strain isolated from a Qatari man in London in 2012 who was one of the first patients to come down with what has since been named Middle East respiratory syndrome-related coronavirus (MERS-CoV). The Qatari patient had traveled to Saudi Arabia from Qatar. He returned to Qatar, but when he fell ill, he traveled to London for treatment. The United Kingdom's Health Protection Agency (HPA) named the virus.[1]
Virology
Phylogenetic analysis demonstrated that London1 is a Betacoronavirus with a close relationship to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5. It was found that the virus nucleic acid fragment identified in the isolate from the Qatari-London patient is derived from a coronavirus that was distinct from all coronaviruses previously identified.[2]
Further reading
- 10.1371/journal.ppat.1003595 . Emergence of the Middle East Respiratory Syndrome Coronavirus . 2013 . Racaniello . Vincent . Coleman . Christopher M. . Frieman . Matthew B. . PLOS Pathogens . 9 . 9 . e1003595 . 24039577 . 3764217 . free .
Notes and References
- Web site: Robert . Roos . UK agency picks name for new coronavirus isolate . Centers for Infectious Disease Research and Policy . September 25, 2012 .
- 23078800 . Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012 . European Centre for Disease Prevention and Control (ECDC) - Surveillance and Communication Unit . 2012 . Chand . MA . Brown . CS . Aarons . E . Tong . C . Langrish . C . Hoschler . K . Brown . K . Galiano . M . Myers . R . Pebody . Green . HK . Boddington . NL . Gopal . R . Price . N . Newsholme . W . Drosten . C . Fouchier . RA . Zambon . M . 17 . 40 . 20290 . Euro Surveillance.
