| Official Name: | Locke Station, Mississippi |
| Pushpin Map: | Mississippi#USA |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Mississippi |
| Subdivision Type2: | Counties |
| Subdivision Name2: | Panola and Quitman |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 161 |
| Coordinates: | 34.2786°N -90.1556°W |
| Area Code: | 662 |
| Blank Name: | GNIS feature ID |
| Blank Info: | 685692[1] |
Locke Station is an unincorporated community in Panola and Quitman counties, Mississippi, United States. Locke Station is located along U.S. Route 278 and Mississippi Highway 6, east of Marks.