| Little River | |
| Pushpin Map: | New Hampshire#USA |
| Pushpin Map Size: | 250 px |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New Hampshire |
| Subdivision Type3: | Counties |
| Subdivision Name3: | Rockingham, Strafford |
| Subdivision Type4: | Towns |
| Subdivision Name4: | Nottingham, Lee |
| Length: | 10.4miles |
| Source1: | Mendums Pond |
| Source1 Location: | Nottingham |
| Source1 Coordinates: | 43.1631°N -71.0683°W |
| Source1 Elevation: | 225feet |
| Mouth: | Lamprey River |
| Mouth Location: | Lee |
| Mouth Coordinates: | 43.1117°N -71.0075°W |
| Mouth Elevation: | 65feet |
| Tributaries Right: | Pea Porridge Brook |
The Little River is a 10.4adj=midNaNadj=mid[1] river in southeastern New Hampshire in the United States. It is a tributary of the Lamprey River, part of the Great Bay and Piscataqua River watershed leading to the Atlantic Ocean.
The river rises in Nottingham as the outlet of Mendums Pond. The river flows south, passing through Nottingham Lake, and then east, where it joins the Lamprey River near the town center of Lee.