| Little River | |
| Pushpin Map: | New Hampshire#USA |
| Pushpin Map Size: | 250 px |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New Hampshire |
| Subdivision Type3: | County |
| Subdivision Name3: | Rockingham |
| Subdivision Type4: | Towns |
| Subdivision Name4: | Brentwood, Exeter |
| Length: | 7.2miles |
| Source1 Location: | Brentwood |
| Source1 Coordinates: | 43.0086°N -71.0233°W |
| Source1 Elevation: | 125feet |
| Mouth: | Exeter River |
| Mouth Location: | Exeter |
| Mouth Coordinates: | 42.9742°N -70.9436°W |
| Mouth Elevation: | 25feet |
| Tributaries Left: | Bloody Brook |
| Tributaries Right: | Dudley Brook, Scamen Brook |
The Little River is a 7.2adj=midNaNadj=mid[1] stream largely in the town of Exeter in Rockingham County, New Hampshire, United States. It is a tributary of the Exeter River, part of the Great Bay/Piscataqua River watershed in the New Hampshire Seacoast region. The river should not be confused with the Little River of Brentwood and Kingston, another Exeter River tributary less than 3miles to the west.
The Little River rises in the northeastern corner of Brentwood and flows east, quickly entering the town limits of Exeter. The river flows southeast through wetlands and past low hills, passing through Colcord Pond just west of the downtown part of Exeter. The river flows into the Exeter River at the southern edge of the campus of Phillips Exeter Academy.