Little Loyalsock Creek is the major tributary of Loyalsock Creek in Lycoming and Sullivan counties, Pennsylvania, United States. The creek is long.[1] Via Loyalsock Creek and the West Branch Susquehanna River, it is part of the Susquehanna River drainage basin, and waters from it flow ultimately into the Chesapeake Bay.
Little Loyalsock Creek has its source near the borough of Dushore in Sullivan County, then flows west-southwest to its confluence with Loyalsock Creek in the borough of Forksville.