List of systems biology visualization software explained

Online software

NameDescription Site
GESTALT Workbenchgraphical workbench for analysis of large-scale genomic sequence datahttp://db.systemsbiology.net/gestalt/
N-Browseinteractive graphical browser for biological networkshttp://aquila.bio.nyu.edu/NBrowse2/NBrowse.html
NetPathcurated resource of human signal transduction pathwayshttp://www.netpath.org/
MEGAfree, online, open-source, phylogenetic analysis, drawing dendrograms etc.http://www.megasoftware.net/
REACTOMEfree, online, open-source, curated pathway database encompassing many areas of human biologyhttp://www.reactome.org/
WikiPathwayscurate biological pathwayshttp://www.wikipathways.org/
MetaboMAPSvisualize omics data on shared metabolic pathways [1] https://metabomaps.brenda-enzymes.org/

Applications

NameDescription OSLicenseSite
BioTapestryinteractive tool for building, visualizing, and simulating genetic regulatory networksmultiplatform (Java-based)LGPLhttp://www.biotapestry.org
Cytoscapedata integration, network visualization, and analysismultiplatform (Java-based)LGPLhttp://www.cytoscape.org/
GenMAPPvisualize and analyze genomic data in the context of pathwaysWindowsApache Licensehttp://www.genmapp.org/
MATLABtool for modeling, simulating, and analyzing dynamic biological systemsWindows, Linux, macOSProprietaryhttps://www.mathworks.com/products/simbiology.html
MEGAfree, online, open-source, phylogenetic analysis, drawing dendrograms etc.Windows/DOS-Win/Mac/LinuxSharewarehttp://www.megasoftware.net/
PathVisiotool for displaying and editing biological pathwaysmultiplatform (Java-based)Apache Licensehttp://www.pathvisio.org/
InCroMAPtool for the integration of omics data and joint visualization of experimental data in pathwaysmultiplatform (Java-based)LGPLhttp://www.cogsys.cs.uni-tuebingen.de/software/InCroMAP/
Pathviewpathway based data integration and visualization, easy to use and integrate into pathway analysismultiplatform (R/Bioconductor)GPLhttp://pathview.r-forge.r-project.org/ http://bioconductor.org/packages/release/bioc/html/pathview.html
SBMLDiagrams[2] Python API to display and edit SBML layout/render extension multiplatform MIT https://github.com/sys-bio/SBMLDiagrams
Systripanalysis of time-series data in the context of biological networksWindows, LinuxLGPL, GPLhttps://tulip.labri.fr/TulipDrupal/?q=systrip

Notes and References

  1. 10.12688/f1000research.23427.2. MetaboMAPS: Pathway sharing and multi-omics data visualization in metabolic context. 2020. Koblitz. Julia. Schomburg. Dietmar. Neumann-Schaal. Meina. F1000Research. 9. 288. 32765840. 7383707 . free .
  2. Xu . Jin . Jiang . Jessie . Sauro . Herbert M . SBMLDiagrams: a python package to process and visualize SBML layout and render . Bioinformatics . 1 January 2023 . 39 . 1 . btac730 . 10.1093/bioinformatics/btac730. 36370074 . 9805581 .